Could palmitoylethanolamide (PEA) help you?

November 14, 2018

Could palmitoylethanolamide (PEA) help you?

A new approach for pain and inflammation?

There’s a promising new medication that may help to relieve painful symptoms and possibly reduce reliance on other drugs. Better still, it has virtually no side effects.

It’s called PEA (an abbreviation of its chemical name, palmitoylethanolamide).


The chemical structure of palmitoylethanolamide (PEA)

What is PEA?

PEA is a substance that occurs naturally in low levels in your body and in foods that you eat. It is found, for example, in egg yolks and soybeans.

It’s a fatty acid amide, a class of chemicals that are natural components of the membranes of your body’s cells. It is an active component, however, playing an inhibitory role against the body’s pain and inflammatory processes.

Research suggests that in conditions of chronic pain and inflammation, PEA levels may be reduced and unable to carry out their normal function. Supplementation of PEA (at levels much higher than those found in foods) overcomes this shortfall, often improving pain and inflammation.

What conditions might PEA treat?

In recent years, preclinical and clinical studies have shown PEA to be potentially useful in a wide range of therapeutic areas, including:

(Click on the links to read selected clinical studies and reviews of studies)

It is important to note that PEA is a relatively new therapy, and we don’t yet know if it is equally effective in all conditions and pain states. As a result, it is recommended that it be first taken in combination with one’s existing medications, to reduce their dosages, to reduce their unpleasant side effects, or to reduce or prevent breakthrough episodes. If sufficiently effective, it could then be tried as a primary treatment.

Really? No side effects?

In all the studies undertaken by scientists so far, PEA has been found to be remarkably free of side effects—even at relatively high doses.

How to take PEA

Although PEA is available for purchase without a prescription, we highly recommend that you consult with your doctor before taking it.

PEA is available from Border Compounding Pharmacy as 300mg capsules, but we can also reformulate it as needed to suit your needs.

A typical dosage for pain would be 1 or 2 capsules taken twice daily (600-1200mg total daily dosage). It is sometimes taken at the higher dose initially, for the first 3-6 weeks, then reduced to the lower dose. Like many analgesics, it may not work immediately. It is usually effective after 1-3 weeks of dosing, but treatment should be ceased if no benefit is seen after 3 months.

For dosages in other conditions, please consult our pharmacists.

How to get PEA

Please contact us with any questions, or to make your order.

Leave a comment

Comments will be approved before showing up.

Also in News and Posts

The BCP Acne Regimen
The BCP Acne Regimen

January 22, 2019

Keeping bacteria happy and in natural harmony is critical for the health of the skin and treating acne. If any of these 500 strains of bacteria are disrupted, then the skin becomes more alkaline and an overgrowth of one of the previously good strains of bacteria becomes a problem. Other bacteria and fungi that don’t normally live on the skin are also given an opportunity to colonise – these are the Bad Bacteria!

Continue Reading


January 15, 2019

Melatonin - a regulator of day/night rhythms[/caption] Melatonin is an endogenously produced hormone that is present in animals, plants and microbes. In mammals, melatonin is secreted by the pineal gland in the brain. Initially melatonin was discovered as the regulator of circadian rhythm and sleep, however its uses and roles within the body have been shown to go far beyond this.

Continue Reading

Omeprazole for infant reflux and colic
Omeprazole for infant reflux and colic

January 15, 2019

Omeprazole belongs to a class of medications called proton pump inhibitors (PPIs). The main action of PPIs is a pronounced and long-lasting reduction of gastric (stomach) acid production. They are the most potent inhibitors of acid secretion available. The maximum effectiveness of omeprazole occurs around two hours after administration, lasting for up to three days. However, stomach pain from certain conditions may not ease for several days. If symptoms persist, a doctor should be consulted. 

Continue Reading


Border Compounding Pharmacy

We would love to keep you up to date with what’s happening in our store and all the new exciting products we are formulating.